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1

Of CARs and TRUCKs: chimeric antigen receptor (CAR) T cells engineered with an inducible cytokine to modulate the tumor stroma

Chmielewski, Markus, Hombach, Andreas A., Abken, Hinrich

Journal:

Immunological Reviews

Year:

2014

Language:

english

File:

PDF, 198 KB

english, 2014

2

An Empirical Evaluation of Value at Risk by Scenario Simulation

Journal:

The Journal of Derivatives

Year:

2000

Language:

english

File:

PDF, 229 KB

english, 2000

3

CAR–T cells and solid tumors: tuning T cells to challenge an inveterate foe

David E. Gilham, Reno Debets, Martin Pule, Robert E. Hawkins, Hinrich Abken

Journal:

Trends in Molecular Medicine

Year:

2012

Language:

english

File:

PDF, 460 KB

english, 2012

4

CAR T cells transform to trucks: chimeric antigen receptor–redirected T cells engineered to deliver inducible IL-12 modulate the tumour stroma to combat cancer

Markus Chmielewski, Hinrich Abken

Journal:

Cancer Immunology, Immunotherapy

Year:

2012

Language:

english

File:

PDF, 461 KB

english, 2012

5

TRUCKs: the fourth generation of CARs

Chmielewski, Markus, Abken, Hinrich

Journal:

Expert Opinion on Biological Therapy

Year:

2015

Language:

english

File:

PDF, 430 KB

english, 2015

6

Adoptive therapy with CAR redirected T cells: the challenges in targeting solid tumors

Journal:

Year:

2015

Language:

english

File:

PDF, 2.67 MB

english, 2015

7

CAR T Cells Releasing IL-18 Convert to T-Bet high FoxO1 low Effectors that Exhibit Augmented Activity against Advanced Solid Tumors

Chmielewski, Markus, Abken, Hinrich

Journal:

Year:

2017

Language:

english

File:

PDF, 3.79 MB

english, 2017

8

Of chimeric antigen receptors and antibodies: OX40 and 41BB costimulation sharpen up T cell-based immunotherapy of cancer

Hombach, Andreas A, Abken, Hinrich

Journal:

Year:

2013

Language:

english

File:

PDF, 820 KB

english, 2013

9

Designer-T-Zellen: Können T-Zellen mit definierter Spezifität die adoptive Immuntherapie zum Erfolg führen?

Journal:

Transfusionsmedizin - Immunhämatologie Hämotherapie Immungenetik Zelltherapie

Year:

2014

File:

PDF, 436 KB

2014

10

The growing world of CAR T cell trials: a systematic review

Holzinger, Astrid, Barden, Markus, Abken, Hinrich

Journal:

Cancer Immunology, Immunotherapy

Year:

2016

Language:

english

File:

PDF, 610 KB

english, 2016

11

CD28-ζ CAR T Cells Resist TGF-β Repression through IL-2 Signaling, Which Can Be Mimicked by an Engineered IL-7 Autocrine Loop

Golumba-Nagy, Viktória, Kuehle, Johannes, Hombach, Andreas A., Abken, Hinrich

Journal:

Molecular Therapy

Year:

2018

Language:

english

File:

PDF, 2.50 MB

english, 2018

12

SUCCESSFUL USE OF ELECTROCONVULSIVE THERAPY FOR THE TREATMENT OF NEUROPSYCHIATRIC MANIFESTATIONS OF DEMENTIA WITH LEWY BODIES

Janjua, A. Umair, Dhingra, Amitha, Abken, Elise, Hermida, Adriana

Journal:

American Journal of Geriatric Psychiatry

Year:

2019

Language:

english

File:

PDF, 44 KB

english, 2019

13

IL7-IL12 Engineered Mesenchymal Stem Cells (MSCs) Improve A CAR T Cell Attack Against Colorectal Cancer Cells

Hombach, Andreas A., Geumann, Ulf, GÃ¼nther, Christine, Hermann, Felix G., Abken, Hinrich

Journal:

Year:

2020

File:

PDF, 2.65 MB

2020

14

A cadmium-free CuInSe2 superstrate solar cell fabricated by electrodeposition using a ITO/In2Se3/CuInSe2/Au structure

A. Kampmann, A. Abken, G. Leimkühler, J. Rechid, V. Sittinger, T. Wietler, R. Reineke-Koch

Journal:

Progress in Photovoltaics: Research and Applications

Year:

1999

Language:

english

File:

PDF, 135 KB

english, 1999

15

Tumor-infiltrating lymphocytes isolated from a Ki-1–positive large cell lymphoma of the skin. Phenotypic characterization and analysis of cytokine secretion

Uwe Reinhold, Hinrich Abken, Sylvia Kukel, Barbara Goeden, Manfred Uerlich, Ute Neumann, Hans-Wilhelm Kreysel

Journal:

Year:

1991

Language:

english

File:

PDF, 613 KB

english, 1991

16

An entirely humanized CD3 ζ-chain signaling receptor that directs peripheral blood t cells to specific lysis of carcinoembryonic antigen–positive tumor cells

Andreas Hombach, Claudia Schneider, Dagmar Sent, Dimitra Koch, Ralph A. Willemsen, Volker Diehl, Wolfgang Kruis, Reinder L. Bolhuis, Christoph Pohl, Hinrich Abken

Journal:

International Journal of Cancer

Year:

2000

Language:

english

File:

PDF, 100 KB

english, 2000

17

Key Aspects of CdTe/CdS Solar Cells

K. Durose, D. Boyle, A. Abken, C.J. Ottley, P. Nollet, S. Degrave, M. Burgelman, R. Wendt, J. Beier, D. Bonnet

Journal:

physica status solidi (b)

Year:

2002

Language:

english

File:

PDF, 2.40 MB

english, 2002

18

An analysis of intra-market spreads in heating oil futures

Journal:

Journal of Futures Markets

Year:

1989

Language:

english

File:

PDF, 585 KB

english, 1989

19

An analysis of intra-market spreads in heating oil futures

Journal:

Journal of Futures Markets

Year:

1989

Language:

english

File:

PDF, 585 KB

english, 1989

20

Anti-CD30-IL-12 antibody-cytokine fusion protein that induces IFN-γ secretion of T cells and NK cell-mediated lysis of Hodgkin's lymphoma-derived tumor cells

Claudia Heuser, Volker Diehl, Hinrich Abken, Andreas Hombach

Journal:

International Journal of Cancer

Year:

2003

Language:

english

File:

PDF, 153 KB

english, 2003

21

Anti-CD30-scFv-Fc-IL-2 antibody-cytokine fusion protein that induces resting NK cells to highly efficient cytolysis of Hodgkin's lymphoma derived tumour cells

Claudia Heuser, Stefan Guhlke, Alexander Matthies, Hans Bender, Stefan Barth, Volker Diehl, Hinrich Abken, Andreas Hombach

Journal:

International Journal of Cancer

Year:

2004

Language:

english

File:

PDF, 235 KB

english, 2004

22

Simultaneous targeting of IL2 and IL12 to Hodgkin's lymphoma cells enhances activation of resting NK cells and tumor cell lysis

Andreas Hombach, Claudia Heuser, Hinrich Abken

Journal:

International Journal of Cancer

Year:

2005

Language:

english

File:

PDF, 139 KB

english, 2005

23

B7-1 and B7-2 act differentially in the induction of a T cell response: Their impact for a HLA-matched and HLA-mismatched anti-tumor immunotherapy

Kai Kronfeld, Hinrich Abken, Barbara Seliger

Journal:

International Journal of Cancer

Year:

2005

Language:

english

File:

PDF, 148 KB

english, 2005

24

Costimulation by chimeric antigen receptors revisited the T cell antitumor response benefits from combined CD28-OX40 signalling

Andreas A. Hombach, Hinrich Abken

Journal:

International Journal of Cancer

Year:

2011

Language:

english

File:

PDF, 830 KB

english, 2011

25

Can combined T-cell- and antibody-based immunotherapy outsmart tumor cells?

Hinrich Abken, Andreas Hombach, Uwe Reinhold, Soldano Ferrone

Journal:

Immunology Today

Year:

1998

Language:

english

File:

PDF, 10.72 MB

english, 1998

26

Chemical stability of sputtered Mo/Sb2Te3 and Ni/Sb2Te3 layers in view of stable back contacts for CdTe/CdS thin film solar cells

Journal:

Solar Energy Materials and Solar Cells

Year:

2002

Language:

english

File:

PDF, 531 KB

english, 2002

27

The CD7− T cell subset represents the majority of IL-5-secreting cells within CD4+CD45RA− T cells

U. REINHOLD, L. LIU, J. SESTERHENN, S. SCHNAUTZ, H. ABKEN

Journal:

Clinical & Experimental Immunology

Year:

1996

Language:

english

File:

PDF, 360 KB

english, 1996

28

Accumulation of CD4+CD7− T cells in inflammatory skin lesions: evidence for preferential adhesion to vascular endothelial cells

L. Liu, H. Abken, C. Pföhler, G. Rappl, W. Tilgen, U. Reinhold

Journal:

Clinical & Experimental Immunology

Year:

2000

Language:

english

File:

PDF, 113 KB

english, 2000

29

CD7-negative T cells represent a separate differentiation pathway in a subset of post-thymic helper T cells

U. REINHOLD, L. LIU, J. SESTERHENN, H. ABKEN

Journal:

Year:

1996

Language:

english

File:

PDF, 419 KB

english, 1996

30

Specific Lysis of Melanoma Cells by Receptor Grafted T Cells is Enhanced by Anti-Idiotypic Monoclonal Antibodies Directed to the scFv Domain of the Receptor

Reinhold, Uwe, Liu, Lide, Lüdtke-Handjery, Hans-Christian, Heuser, Claudia, Hombach, Andreas, Wang, Xinhui, Tilgen, Wolfgang, Ferrone, Soldano, Abken, Hinrich

Journal:

The Journal of Investigative Dermatology

Year:

1999

Language:

english

File:

PDF, 428 KB

english, 1999

31

Dermal Fibroblasts Sustain Proliferation of Activated T Cells via Membrane-Bound Interleukin-15 upon Long-Term Stimulation with Tumor Necrosis Factor-alpha

Rappl, Gunter, Kapsokefalou, Anna, Heuser, Claudia, Ugurel, Selma, Tilgen, Wolfgang, Reinhold, Uwe, Abken, Hinrich

Journal:

The Journal of Investigative Dermatology

Year:

2001

Language:

english

File:

PDF, 307 KB

english, 2001

32

Antibody-based immunoreceptors: the impact of signalling domain, binding affinity and costimulation

A Hombach, C Heuser, H Abken

Journal:

Cancer Cell International

Year:

2004

Language:

english

File:

PDF, 204 KB

english, 2004

33

Targeting of tumor cells expressing the prostate stem cell antigen (PSCA) using genetically engineered T-cells

Agnieszka Morgenroth, Marc Cartellieri, Marc Schmitz, Serap Günes, Bernd Weigle, Michael Bachmann, Hinrich Abken, Ernst Peter Rieber, Achim Temme

Journal:

Year:

2007

Language:

english

File:

PDF, 340 KB

english, 2007

34

Costimulation tunes tumor-specific activation of redirected T cells in adoptive immunotherapy

Andreas Hombach, Hinrich Abken

Journal:

Cancer Immunology, Immunotherapy

Year:

2007

Language:

english

File:

PDF, 312 KB

english, 2007

35

Adoptive T-Zell-Therapie des Rhabdomyosarkoms

K. Simon-Keller, A. Paschen, S. Eichmüller, S. Gattenlöhner, S. Barth, E. Koscielniak, I. Leuschner, P. Stöbel, A. Hombach, H. Abken, A. Marx

Journal:

Year:

2010

Language:

german

File:

PDF, 515 KB

german, 2010

36

The Analysis of Tyrosinase-Specific mRNA in Blood Samples of Melanoma Patients by RT-PCR Is Not a Useful Test for Metastic Tumor Progression.

Reinhold, Uwe, Ludtke-Handjery, Hans-Christian, Schnautz, Sylvia, Kreysel, Hans-Wilhelm, Abken, Hinrich

Journal:

The Journal of Investigative Dermatology

Year:

1997

File:

PDF, 1.23 MB

1997

37

Purification and properties of an F420H2 dehydrogenase from Methanosarcina mazei Gö1

Hans-Jörg Abken, Uwe Deppenmeier

Journal:

FEMS Microbiology Letters

Year:

1997

Language:

english

File:

PDF, 542 KB

english, 1997

38

Transfer of mRNA encoding recombinant immunoreceptors reprograms CD4+ and CD8+ T cells for use in the adoptive immunotherapy of cancer

Birkholz, K, Hombach, A, Krug, C, Reuter, S, Kershaw, M, Kämpgen, E, Schuler, G, Abken, H, Schaft, N, Dörrie, J

Journal:

Year:

2009

Language:

english

File:

PDF, 289 KB

english, 2009

39

Redirecting human CD4+CD25+ regulatory T cells from the peripheral blood with pre-defined target specificity

Hombach, A A, Kofler, D, Rappl, G, Abken, H

Journal:

Year:

2009

Language:

english

File:

PDF, 407 KB

english, 2009

40

CD28 cosignalling does not affect the activation threshold in a chimeric antigen receptor-redirected T-cell attack

Chmielewski, M, Hombach, A A, Abken, H

Journal:

Year:

2010

Language:

english

File:

PDF, 643 KB

english, 2010

41

Adoptive immunotherapy with genetically engineered T cells: modification of the IgG1 Fc ‘spacer’ domain in the extracellular moiety of chimeric antigen receptors avoids ‘off-target’ activation and unintended initiation of an innate immune response

Hombach, A, Hombach, A A, Abken, H

Journal:

Year:

2010

Language:

english

File:

PDF, 590 KB

english, 2010

42

Autocrine proliferating B cells are susceptible to terminal differentiation and apoptosis

Fluck, Juliane, Schachtschneider, Susanne, Abken, Hinrich

Journal:

Cell Death & Differentiation

Year:

1997

Language:

english

File:

PDF, 424 KB

english, 1997

43

The CD7− subset of CD4+ memory T cells is prone to accelerated apoptosis that is prevented by interleukin-15 (IL-15)

Rappl, G, Abken, H, Hasselmann, D O, Tilgen, W, Ugurel, S, Reinhold, U

Journal:

Cell Death & Differentiation

Year:

2001

Language:

english

File:

PDF, 163 KB

english, 2001

44

A chimeric receptor that selectively targets membrane-bound carcinoembryonic antigen (mCEA) in the presence of soluble CEA

Hombach, A, Koch, D, Sircar, R, Heuser, C, Diehl, V, Kruis, W, Pohl, C, Abken, H

Journal:

Year:

1999

Language:

english

File:

PDF, 188 KB

english, 1999

45

T cell activation by recombinant FcεRI γ-chain immune receptors: an extracellular spacer domain impairs antigen-dependent T cell activation but not antigen recognition

Hombach, A, Heuser, C, Gerken, M, Fischer, B, Lewalter, K, Diehl, V, Pohl, C, Abken, H

Journal:

Year:

2000

Language:

english

File:

PDF, 235 KB

english, 2000

46

T cells engrafted with a recombinant anti-CD30 receptor target autologous CD30+ cutaneous lymphoma cells

Hombach, A, Muche, J M, Gerken, M, Gellrich, S, Heuser, C, Pohl, C, Sterry, W, Abken, H

Journal:

Year:

2001

Language:

english

File:

PDF, 151 KB

english, 2001

47

T-cell activation by recombinant immunoreceptors: Impact of the intracellular signalling domain on the stability of receptor expression and antigen-specific activation of grafted T cells

Heuser, C, Hombach, A, Lösch, C, Manista, K, Abken, H

Journal:

Year:

2003

Language:

english

File:

PDF, 496 KB

english, 2003

48

Electrodeposition of SbxTeylayers and chemical stability of Mo/Sb2Te3systems

Journal:

Journal of Materials Science Letters

Year:

2002

Language:

english

File:

PDF, 127 KB

english, 2002

49

T cells redirected by a CD3ζ chimeric antigen receptor can establish self-antigen-specific tumour protection in the long term

Chmielewski, M, Rappl, G, Hombach, A A, Abken, H

Journal:

Year:

2013

Language:

english

File:

PDF, 748 KB

english, 2013

50

Regulatory T cells with reduced repressor capacities are extensively amplified in pulmonary sarcoid lesions and sustain granuloma formation

Gunter Rappl, Stefan Pabst, Dagmar Riemann, Annette Schmidt, Claudia Wickenhauser, Wolfgang Schütte, Andreas A. Hombach, Barbara Seliger, Christian Grohé, Hinrich Abken

Journal:

Clinical Immunology

Year:

2011

Language:

english

File:

PDF, 1.41 MB

english, 2011

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